Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABA(A) Receptors by Propofol

ABSTRACT: BACKGROUND: Propofol is a sedative agent that at clinical concentrations acts by allosterically activating or potentiating the γ-aminobutyric acid type A (GABA(A)) receptor. Mutational, modeling, and photolabeling studies with propofol and its analogues have identified potential interactio...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Eaton, Megan M., Germann, Allison L., Arora, Ruby, Cao, Lily Q., Gao, Xiaoyi, Shin, Daniel J., Wu, Albert, Chiara, David C., Cohen, Jonathan B., Steinbach, Joe Henry, Evers, Alex S., Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050400/
https://ncbi.nlm.nih.gov/pubmed/26830963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666160202121319
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