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GABA Type A Receptor Activation in the Allosteric Coagonist Model Framework: Relationship between EC(50) and Basal Activity
The concerted transition model for multimeric proteins is a simple formulation for analyzing the behavior of transmitter-gated ion channels. We used the model to examine the relationship between the EC(50) for activation of the GABA type A (GABA(A)) receptor by the transmitter GABA and basal activit...
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| Publicado en: | Mol Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5749490/ https://ncbi.nlm.nih.gov/pubmed/29150461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.110569 |
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