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Applying the Monod-Wyman-Changeux Allosteric Activation Model to Pseudo–Steady-State Responses from GABA(A) Receptors
The Monod-Wyman-Changeux (MWC) cyclic model was described as a kinetic scheme to explain enzyme function and modulation more than 50 years ago and was proposed as a model for understanding the activation of transmitter-gated channels soon afterward. More recently, the MWC model has been used to desc...
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| Publié dans: | Mol Pharmacol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277929/ https://ncbi.nlm.nih.gov/pubmed/30333132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.113787 |
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