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Enhancement of Muscimol Binding and Gating by Allosteric Modulators of the GABA(A) Receptor: Relating Occupancy to State Functions
Muscimol is a psychoactive isoxazole derived from the mushroom Amanita muscaria and a potent orthosteric agonist of the GABA(A) receptor. The binding of [(3)H]muscimol has been used to evaluate the distribution of GABA(A) receptors in the brain, and studies of modulation of [(3)H]muscimol binding by...
Shranjeno v:
| izdano v: | Mol Pharmacol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7472144/ https://ncbi.nlm.nih.gov/pubmed/32873746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.000066 |
| Oznake: |
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