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Analysis of Modulation of the ρ1 GABA(A) Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites

The ρ1 GABA(A) receptor is prominently expressed in the retina and is present at lower levels in several brain regions and other tissues. Although the ρ1 receptor is insensitive to many anesthetic drugs that modulate the heteromeric GABA(A) receptor, it maintains a rich and multifaceted steroid phar...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Germann, Allison L., Reichert, David E., Burbridge, Ariel B., Pierce, Spencer R., Evers, Alex S., Steinbach, Joe Henry, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472123/
https://ncbi.nlm.nih.gov/pubmed/32675382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119842
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