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Analysis of Modulation of the ρ1 GABA(A) Receptor by Combinations of Inhibitory and Potentiating Neurosteroids Reveals Shared and Distinct Binding Sites

The ρ1 GABA(A) receptor is prominently expressed in the retina and is present at lower levels in several brain regions and other tissues. Although the ρ1 receptor is insensitive to many anesthetic drugs that modulate the heteromeric GABA(A) receptor, it maintains a rich and multifaceted steroid phar...

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Publicat a:Mol Pharmacol
Autors principals: Germann, Allison L., Reichert, David E., Burbridge, Ariel B., Pierce, Spencer R., Evers, Alex S., Steinbach, Joe Henry, Akk, Gustav
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472123/
https://ncbi.nlm.nih.gov/pubmed/32675382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119842
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