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Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids

The ρ1 GABA receptor is inhibited by a number of neuroactive steroids. A previous study (J Pharmacol Exp Ther 323:236–247, 2007) focusing on the electrophysiological effects of inhibitory steroids on the ρ1 receptor found that steroid inhibitors could be divided into three major groups based on how...

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Detalhes bibliográficos
Main Authors: Li, Ping, Khatri, Alpa, Bracamontes, John, Weiss, David S., Steinbach, Joe Henry, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2845946/
https://ncbi.nlm.nih.gov/pubmed/20061447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.062885
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