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A neurosteroid potentiation site can be moved among GABA(A) receptor subunits
Endogenous neurosteroids are among the most potent and efficacious potentiators of activation of GABA(A) receptors. It has been proposed that a conserved glutamine residue in the first membrane-spanning region (TM1 region) of the α subunits is required for binding of potentiating neurosteroids. Muta...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3528988/ https://ncbi.nlm.nih.gov/pubmed/22988137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.237255 |
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