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The Actions of Drug Combinations on the GABA(A) Receptor Manifest as Curvilinear Isoboles of Additivity

Drug interactions are often analyzed in terms of isobolograms. In the isobologram, the line connecting the axial points corresponding to the concentrations of two different drugs that produce an effect of the same magnitude is termed an isobole of additivity. Although the isobole of additivity can b...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Shin, Daniel J., Germann, Allison L., Steinbach, Joe Henry, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5635521/
https://ncbi.nlm.nih.gov/pubmed/28790148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.109595
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