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Analysis of GABA(A) Receptor Activation by Combinations of Agonists Acting at the Same or Distinct Binding Sites

Under both physiologic and clinical conditions GABA(A) receptors are exposed to multiple agonists, including the transmitter GABA, endogenous or exogenous neuroactive steroids, and various GABAergic anesthetic and sedative drugs. The functional output of the receptor reflects the interplay among all...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Shin, Daniel J., Germann, Allison L., Covey, Douglas F., Steinbach, Joe Henry, Akk, Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277923/
https://ncbi.nlm.nih.gov/pubmed/30337372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.113464
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