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Activation and block of recombinant GABA(A) receptors by pentobarbitone: a single-channel study

1. Recombinant GABA(A) receptors (α1β2γ2L) were transiently expressed in HEK 293 cells. We have investigated activation and block of these receptors by pentobarbitone (PB) using cell-attached single-channel patch clamp. 2. Clusters of single-channel activity elicited by 500 μM PB were analysed to es...

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Detalhes bibliográficos
Main Authors: Akk, Gustav, Steinbach, Joe Henry
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572086/
https://ncbi.nlm.nih.gov/pubmed/10807661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0703335
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