Neurosteroid Analog Photolabeling of a Site in the Third Transmembrane Domain of the β3 Subunit of the GABA(A) Receptor

Accumulated evidence suggests that neurosteroids modulate GABA(A) receptors through binding interactions with transmembrane domains. To identify these neurosteroid binding sites directly, a neurosteroid-analog photolabeling reagent, (3α,5β)-6-azi-pregnanolone (6-AziP), was used to photolabel membran...

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Bibliografiset tiedot
Päätekijät: Chen, Zi-Wei, Manion, Brad, Townsend, R. Reid, Reichert, David E., Covey, Douglas F., Steinbach, Joe Henry, Sieghart, Werner, Fuchs, Karoline, Evers, Alex S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Pharmacology and Experimental Therapeutics 2012
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422701/
https://ncbi.nlm.nih.gov/pubmed/22648971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078410
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