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Kinetic and Structural Determinants for GABA-A Receptor Potentiation by Neuroactive Steroids
Endogenous neurosteroids and synthetic neuroactive steroid analogs are among the most potent and efficacious potentiators of the mammalian GABA-A receptor. The compounds interact with one or more sites on the receptor leading to an increase in the channel open probability through a set of changes in...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers Ltd.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2866458/ https://ncbi.nlm.nih.gov/pubmed/20808543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/157015910790909458 |
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