Slow Actions of Neuroactive Steroids at GABA(A) Receptors

Neuroactive steroids are potent and efficacious modulators of GABA(A) receptor activity and are potent sedatives and anesthetics. These positive modulators of GABA(A) receptors both potentiate the actions of GABA at the receptor and, at higher concentrations, directly gate the channel. The contribut...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Shu, Hong-Jin, Eisenman, Lawrence N., Jinadasa, Deepani, Covey, Douglas F., Zorumski, Charles F., Mennerick, Steven
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729712/
https://ncbi.nlm.nih.gov/pubmed/15282269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1399-04.2004
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