Slow Actions of Neuroactive Steroids at GABA(A) Receptors

Neuroactive steroids are potent and efficacious modulators of GABA(A) receptor activity and are potent sedatives and anesthetics. These positive modulators of GABA(A) receptors both potentiate the actions of GABA at the receptor and, at higher concentrations, directly gate the channel. The contribut...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Shu, Hong-Jin, Eisenman, Lawrence N., Jinadasa, Deepani, Covey, Douglas F., Zorumski, Charles F., Mennerick, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729712/
https://ncbi.nlm.nih.gov/pubmed/15282269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1399-04.2004
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