Activation and modulation of recombinant glycine and GABA(A) receptors by 4‐halogenated analogues of propofol

Por Germann, Allison L, Shin, Daniel J, Manion, Brad D, Edge, Christopher J, Smith, Edward H, Franks, Nicholas P, Evers, Alex S, Akk, Gustav
Publicado no Br J Pharmacol (2016)

Neurosteroid Analogues. 15. A Comparative Study of the Anesthetic and GABAergic Actions of Alphaxalone, Δ(16)-Alphaxalone and Their Corresponding 17-Carbonitrile Analogues

Por Bandyopadhyaya, Achintya K., Manion, Brad D., Benz, Ann, Taylor, Amanda, Rath, Nigam P., Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2010

Neurosteroid Analogues. 17. Inverted Binding Orientations of Androsterone Enantiomers at the Steroid Potentiation Site on γ-Aminobutyric Acid Type A (GABA(A)) Receptors

Por Krishnan, Kathiresan, Manion, Brad D., Taylor, Amanda, Bracamontes, John, Steinbach, Joseph H., Reichert, David E., Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2012

Neurosteroid Analogues. 16. A new explanation for the lack of anesthetic effects of Δ(16)-alphaxalone and identification of a Δ(17(20)) analogue with potent anesthetic activity

Por Stastna, Eva, Krishnan, Kathiresan, Manion, Brad D., Taylor, Amanda, Rath, Nigam P., Chen, Zi-Wei, Evers, Alex. S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2011

Neurosteroid Analogues. 18. Structure–Activity Studies of ent-Steroid Potentiators of γ-Aminobutyric Acid type A Receptors and Comparison of Their Activities with Those of Alphaxal...

Por Qian, Mingxing, Krishnan, Kathiresan, Kudova, Eva, Li, Ping, Manion, Brad D., Taylor, Amanda, Elias, George, Akk, Gustav, Evers, Alex S., Zorumski, Charles F., Mennerick, Steven, Covey, Douglas F.
Publicado em 2013

A Synthetic 18-Norsteroid Distinguishes between Two Neuroactive Steroid Binding Sites on GABA(A) Receptors

Por Evers, Alex S., Chen, Zi-Wei, Manion, Brad D., Han, Mingcheng, Jiang, Xin, Darbandi-Tonkabon, Ramin, Kable, Tristan, Bracamontes, John, Zorumski, Charles F., Mennerick, Steven, Steinbach, Joe Henry, Covey, Douglas F.
Publicado em 2010

11-TRIFLUOROMETHYL-PHENYLDIAZIRINYL NEUROSTEROID ANALOGUES: POTENT GENERAL ANESTHETICS AND PHOTOLABELING REAGENTS FOR GABA(A) RECEPTORS

Por Chen, Zi-Wei, Wang, Cunde, Krishnan, Kathiresan, Manion, Brad D., Hastings, Randy, Bracamontes, John, Taylor, Amanda, Eaton, Megan M., Zorumski, Charles F., Steinbach, Joseph H., Akk, Gustav, Mennerick, Steven, Covey, Douglas F., Evers, Alex S.
Publicado no Psychopharmacology (Berl) (2014)