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Click chemistry reagent for identification of sites of covalent ligand incorporation in integral membrane proteins
Identifying sites of protein-ligand interaction is important for structure-based drug discovery and understanding protein structure-function relationships. Mass spectrometry (MS) has emerged as a useful tool for identifying residues covalently modified by ligands. Current methods use database search...
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| Publicado no: | Anal Chem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5328583/ https://ncbi.nlm.nih.gov/pubmed/28194953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b05003 |
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