Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling

Voltage-dependent anion channel-1 (VDAC1) is a mitochondrial porin that is implicated in cellular metabolism and apoptosis, and modulated by numerous small molecules including lipids. VDAC1 binds sterols, including cholesterol and neurosteroids such as allopregnanolone. Biochemical and computational...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Biochim Biophys Acta Mol Cell Biol Lipids
Hlavní autoři: Cheng, Wayland W.L., Budelier, Melissa M., Sugasawa, Yusuke, Bergdoll, Lucie, Queralt-Martín, María, Rosencrans, William, Rostovtseva, Tatiana K., Chen, Zi-Wei, Abramson, Jeff, Krishnan, Kathiresan, Covey, Douglas F., Whitelegge, Julian P., Evers, Alex S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681461/
https://ncbi.nlm.nih.gov/pubmed/31176038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2019.06.004
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky