In vivo imaging and biochemical characterization of protease function using fluorescent activity-based probes

Por Edgington, Laura E., Bogyo, Matthew
Publicado em 2013

Functional imaging of proteases: recent advances in the design and application of substrate- and activity- based probes

Por Edgington, Laura E., Verdoes, Martijn, Bogyo, Matthew
Publicado em 2011

Comparative Assessment of Substrates and Activity Based Probes as Tools for Non-Invasive Optical Imaging of Cysteine Protease Activity

Por Blum, Galia, Weimer, Robby M., Edgington, Laura E., Adams, Walter, Bogyo, Matthew
Publicado em 2009

An optimized activity-based probe for the study of caspase-6 activation

Por Edgington, Laura E., van Raam, Bram J., Verdoes, Martijn, Wierschem, Christoph, Salvesen, Guy S., Bogyo, Matthew
Publicado em 2012

Non-invasive optical imaging of apoptosis using caspase-targeted activity based probes

Por Edgington, Laura E., Berger, Alicia B., Blum, Galia, Albrow, Victoria E., Paulick, Margot G., Lineberry, Neil, Bogyo, Matthew
Publicado em 2009

Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo

Por Deu, Edgar, Chen, Ingrid T., Lauterwasser, Erica M. W., Valderramos, Juan, Li, Hao, Edgington, Laura E., Renslo, Adam R., Bogyo, Matthew
Publicado em 2013

Inhibition of cathepsin proteases attenuates migration and sensitizes aggressive N-Myc amplified human neuroblastoma cells to doxorubicin

Por Gangoda, Lahiru, Keerthikumar, Shivakumar, Fonseka, Pamali, Edgington, Laura E., Ang, Ching-Seng, Ozcitti, Cemil, Bogyo, Matthew, Parker, Belinda S., Mathivanan, Suresh
Publicado no Oncotarget (2015)

A non-peptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages

Por Verdoes, Martijn, Edgington, Laura E., Scheeren, Ferenc, Leyva, Melissa, Blum, Galia, Weiskopf, Kipp, Bachmann, Michael H., Ellman, Jonathan A., Bogyo, Matthew
Publicado em 2012

Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe

Por Edgington, Laura E., Verdoes, Martijn, Ortega, Alberto, Withana, Nimali P., Lee, Jiyoun, Syed, Salahuddin, Bachmann, Michael H., Blum, Galia, Bogyo, Matthew
Publicado no J Am Chem Soc (2012)

Treatment of Arthritis by Macrophage Depletion and Immunomodulation: Testing an Apoptosis-Mediated Therapy in a Humanized Death Receptor Mouse Model

Por Li, Jun, Hsu, Hui-Chen, Yang, PingAr, Wu, Qi, Li, Hao, Edgington, Laura E., Bogyo, Matthew, Kimberly, Robert P., Mountz, John D.
Publicado em 2011

The Apoptosis Repressor with a CARD Domain (ARC) Gene Is a Direct Hypoxia-Inducible Factor 1 Target Gene and Promotes Survival and Proliferation of VHL-Deficient Renal Cancer Cells

Por Razorenova, Olga V., Castellini, Laura, Colavitti, Renata, Edgington, Laura E., Nicolau, Monica, Huang, Xin, Bedogni, Barbara, Mills, Edward M., Bogyo, Matthew, Giaccia, Amato J.
Publicado em 2014

Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a (64)Cu-Labeled Activity-Based Probe

Por Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen
Publicado em 2011

Validation of the proteasome as a therapeutic target in Plasmodium using an epoxyketone inhibitor with parasite-specific toxicity

Por Li, Hao, Ponder, Elizabeth L., Verdoes, Martijn, Asbjornsdottir, Kristijana H., Deu, Edgar, Edgington, Laura E., Lee, Jeong Tae, Kirk, Christopher J., Demo, Susan D., Williamson, Kim C., Bogyo, Matthew
Publicado em 2012