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An optimized activity-based probe for the study of caspase-6 activation
While significant efforts have been made to understand the mechanisms of caspase activation during apoptosis, many questions remain regarding how and when the executioner caspases get activated. We describe the design and synthesis of an activity-based probe that labels caspases-3/-6 /-7, allowing d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3314226/ https://ncbi.nlm.nih.gov/pubmed/22444589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.12.021 |
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