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Proliferative versus Apoptotic Functions of Caspase-8 Hetero or Homo: The Caspase-8 Dimer Controls Cell Fate

Caspase-8, the initiator of extrinsically-triggered apoptosis, also has important functions in cellular activation and differentiation downstream of a variety of cell surface receptors. It has become increasingly clear that the heterodimer of caspase-8 with the long isoform of cellular FLIP (FLIP(L)...

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Detalhes bibliográficos
Main Authors: van Raam, Bram J., Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993904/
https://ncbi.nlm.nih.gov/pubmed/21704196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbapap.2011.06.005
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