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Extracellular domains drive homo- but not hetero-dimerization of erbB receptors

Many different growth factor ligands, including epidermal growth factor (EGF) and the neuregulins (NRGs), regulate members of the erbB/HER family of receptor tyrosine kinases. These growth factors induce erbB receptor oligomerization, and their biological specificity is thought to be defined by the...

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Detalhes bibliográficos
Main Authors: Ferguson, Kathryn M., Darling, Paul J., Mohan, Mohita J., Macatee, Timothy L., Lemmon, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC302059/
https://ncbi.nlm.nih.gov/pubmed/10970856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.17.4632
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