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Extracellular domains drive homo- but not hetero-dimerization of erbB receptors

Many different growth factor ligands, including epidermal growth factor (EGF) and the neuregulins (NRGs), regulate members of the erbB/HER family of receptor tyrosine kinases. These growth factors induce erbB receptor oligomerization, and their biological specificity is thought to be defined by the...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Ferguson, Kathryn M., Darling, Paul J., Mohan, Mohita J., Macatee, Timothy L., Lemmon, Mark A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10970856/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.17.4632
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