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Probes to monitor activity of the paracaspase MALT1
The human paracaspase MALT1 plays a central role in NF-κB signaling both as a protease and scaffolding protein. Knocking out MALT1 leads to impaired NF-κB signaling and failure to mount an effective immune response. However, it is unclear to which degree it is the scaffolding function versus the pro...
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| Veröffentlicht in: | Chem Biol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304901/ https://ncbi.nlm.nih.gov/pubmed/25556944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.011 |
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