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Probes to monitor activity of the paracaspase MALT1

The human paracaspase MALT1 plays a central role in NF-κB signaling both as a protease and scaffolding protein. Knocking out MALT1 leads to impaired NF-κB signaling and failure to mount an effective immune response. However, it is unclear to which degree it is the scaffolding function versus the pro...

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Detalhes bibliográficos
Publicado no:Chem Biol
Main Authors: Hachmann, Janna, Edgington-Mitchell, Laura E., Poreba, Marcin, Sanman, Laura E., Drag, Marcin, Bogyo, Matthew, Salvesen, Guy S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4304901/
https://ncbi.nlm.nih.gov/pubmed/25556944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2014.11.011
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