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Non-invasive optical imaging of apoptosis using caspase-targeted activity based probes

Imaging agents that enable direct visualization and quantification of apoptosis in vivo have great potential value for monitoring chemotherapeutic response as well as for early diagnosis and disease monitoring. We describe here the development of fluorescently labeled activity based probes (ABPs) th...

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Detalhes bibliográficos
Main Authors: Edgington, Laura E., Berger, Alicia B., Blum, Galia, Albrow, Victoria E., Paulick, Margot G., Lineberry, Neil, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196344/
https://ncbi.nlm.nih.gov/pubmed/19597506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1938
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