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A non-peptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages
Macrophage infiltration into tumors has been correlated with poor clinical outcome in multiple cancer types. Therefore, new tools to image tumor-associated macrophages could be valuable for diagnosis and prognosis of cancer. Herein we describe the synthesis and characterization of a cathepsin S-dire...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361968/ https://ncbi.nlm.nih.gov/pubmed/22633413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2012.03.012 |
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