A carregar...

Functional Imaging of Legumain in Cancer Using a New Quenched Activity-Based Probe

Legumain is a lysosomal cysteine protease whose biological function remains poorly defined. Legumain activity is up-regulated in most human cancers and inflammatory diseases most likely as the result of high expression in populations of activated macrophages. Within the tumor microenvironment, legum...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Edgington, Laura E., Verdoes, Martijn, Ortega, Alberto, Withana, Nimali P., Lee, Jiyoun, Syed, Salahuddin, Bachmann, Michael H., Blum, Galia, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429797/
https://ncbi.nlm.nih.gov/pubmed/23215039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja307083b
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!