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Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain

Asparaginyl endopeptidase, or legumain, is a lysosomal cysteine protease that was originally identified in plants and later found to be involved in antigen presentation in higher eukaryotes. Legumain is also up-regulated in a number of human cancers and recent studies suggest that it may play import...

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Detalhes bibliográficos
Main Authors: Lee, Jiyoun, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3222276/
https://ncbi.nlm.nih.gov/pubmed/20017516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900232a
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