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Development of near-infrared fluorophore (NIRF)-labeled activity-based probes for in vivo imaging of legumain
Asparaginyl endopeptidase, or legumain, is a lysosomal cysteine protease that was originally identified in plants and later found to be involved in antigen presentation in higher eukaryotes. Legumain is also up-regulated in a number of human cancers and recent studies suggest that it may play import...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3222276/ https://ncbi.nlm.nih.gov/pubmed/20017516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900232a |
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