Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a (64)Cu-Labeled Activity-Based Probe

The papain family of cysteine cathepsins are actively involved in multiple stages of tumorigenesis. Because elevated cathepsin activity can be found in many types of human cancers, they are promising biomarkers that can be used to target radiological contrast agents for tumor detection. However, cur...

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Detalhes bibliográficos
Main Authors: Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221694/
https://ncbi.nlm.nih.gov/pubmed/22132198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028029
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