Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a (64)Cu-Labeled Activity-Based Probe

The papain family of cysteine cathepsins are actively involved in multiple stages of tumorigenesis. Because elevated cathepsin activity can be found in many types of human cancers, they are promising biomarkers that can be used to target radiological contrast agents for tumor detection. However, cur...

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Dettagli Bibliografici
Autori principali: Ren, Gang, Blum, Galia, Verdoes, Martijn, Liu, Hongguang, Syed, Salahuddin, Edgington, Laura E., Gheysens, Olivier, Miao, Zheng, Jiang, Han, Gambhir, Sanjiv Sam, Bogyo, Matthew, Cheng, Zhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3221694/
https://ncbi.nlm.nih.gov/pubmed/22132198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028029
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