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An improved quenched fluorescent probe for imaging of cysteine cathepsin activity

The cysteine cathepsins are a family of proteases that play important roles in both normal cellular physiology and many human diseases. In cancer, the activity of many of the cysteine cathepsins is upregulated and can be exploited for tumor imaging. Here we present the design and synthesis of a new...

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Detaylı Bibliyografya
Asıl Yazarlar: Verdoes, Martijn, Bender, Kristina Oresic, Segal, Ehud, van der Linden, Wouter A., Syed, Salahuddin, Withana, Nimali P., Sanman, Laura E., Bogyo, Matthew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826460/
https://ncbi.nlm.nih.gov/pubmed/23971698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja4056068
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