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Comparative Assessment of Substrates and Activity Based Probes as Tools for Non-Invasive Optical Imaging of Cysteine Protease Activity

Recent advances in the field of non-invasive optical imaging have included the development of contrast agents that report on the activity of enzymatic targets associated with disease pathology. In particular, proteases have proven to be ideal targets for development of optical sensors for cancer. Re...

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Autors principals: Blum, Galia, Weimer, Robby M., Edgington, Laura E., Adams, Walter, Bogyo, Matthew
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712068/
https://ncbi.nlm.nih.gov/pubmed/19636372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006374
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