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Design of cell permeable, fluorescent activity based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain

Asparaginyl endopeptidase (AEP), also known as legumain, is a cysteine protease that has been ascribed roles in antigen presentation yet its exact role in human biology remains poorly understood. We report here the use of a positional scanning combinatorial library of peptide AOMKs containing a P1 a...

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Detalhes bibliográficos
Main Authors: Sexton, Kelly B., Witte, Martin D., Blum, Galia, Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832115/
https://ncbi.nlm.nih.gov/pubmed/17189693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.10.100
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