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Design of cell permeable, fluorescent activity based probes for the lysosomal cysteine protease asparaginyl endopeptidase (AEP)/legumain

Asparaginyl endopeptidase (AEP), also known as legumain, is a cysteine protease that has been ascribed roles in antigen presentation yet its exact role in human biology remains poorly understood. We report here the use of a positional scanning combinatorial library of peptide AOMKs containing a P1 a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sexton, Kelly B., Witte, Martin D., Blum, Galia, Bogyo, Matthew
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1832115/
https://ncbi.nlm.nih.gov/pubmed/17189693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.10.100
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