Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion

BACKGROUND AND PURPOSE: Cardiovascular disease is the leading cause of death worldwide, mainly due to an increasing prevalence of atherosclerosis characterized by inflammatory plaques. Plaques with high levels of macrophage infiltration are considered “vulnerable” while those that do not have signif...

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Publicado en:PLoS One
Autores principales: Abd-Elrahman, Ihab, Kosuge, Hisanori, Wises Sadan, Tommy, Ben-Nun, Yael, Meir, Karen, Rubinstein, Chen, Bogyo, Matthew, McConnell, Michael V., Blum, Galia
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988760/
https://ncbi.nlm.nih.gov/pubmed/27532109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160522
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