Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion

BACKGROUND AND PURPOSE: Cardiovascular disease is the leading cause of death worldwide, mainly due to an increasing prevalence of atherosclerosis characterized by inflammatory plaques. Plaques with high levels of macrophage infiltration are considered “vulnerable” while those that do not have signif...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Abd-Elrahman, Ihab, Kosuge, Hisanori, Wises Sadan, Tommy, Ben-Nun, Yael, Meir, Karen, Rubinstein, Chen, Bogyo, Matthew, McConnell, Michael V., Blum, Galia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988760/
https://ncbi.nlm.nih.gov/pubmed/27532109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160522
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