Cathepsin Activity-Based Probes and Inhibitor for Preclinical Atherosclerosis Imaging and Macrophage Depletion

BACKGROUND AND PURPOSE: Cardiovascular disease is the leading cause of death worldwide, mainly due to an increasing prevalence of atherosclerosis characterized by inflammatory plaques. Plaques with high levels of macrophage infiltration are considered “vulnerable” while those that do not have signif...

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Veröffentlicht in:PLoS One
Hauptverfasser: Abd-Elrahman, Ihab, Kosuge, Hisanori, Wises Sadan, Tommy, Ben-Nun, Yael, Meir, Karen, Rubinstein, Chen, Bogyo, Matthew, McConnell, Michael V., Blum, Galia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988760/
https://ncbi.nlm.nih.gov/pubmed/27532109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160522
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