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Photodynamic Quenched Cathepsin Activity Based Probes for Cancer Detection and Macrophage Targeted Therapy

Elevated cathepsins levels and activities are found in several types of human cancer, making them valuable biomarkers for detection and targeting therapeutics. We designed small molecule quenched activity-based probes (qABPs) that fluoresce upon activity-dependent covalent modification, yielding cel...

詳細記述

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書誌詳細
出版年:Theranostics
主要な著者: Ben-Nun, Yael, Merquiol, Emmanuelle, Brandis, Alexander, Turk, Boris, Scherz, Avigdor, Blum, Galia
フォーマット: Artigo
言語:Inglês
出版事項: Ivyspring International Publisher 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440442/
https://ncbi.nlm.nih.gov/pubmed/26000057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.10854
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