ロード中...
mTORC1 activation in B cells confers impairment of marginal zone microarchitecture by exaggerating cathepsin activity
Mammalian target of rapamycin complex 1 (mTORC1) is a key regulator of cell metabolism and lymphocyte proliferation. It is inhibited by the tuberous sclerosis complex (TSC), a heterodimer of TSC1 and TSC2. Deletion of either gene results in robust activation of mTORC1. Mature B cells reside in the s...
保存先:
| 出版年: | Immunology |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2018
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6231019/ https://ncbi.nlm.nih.gov/pubmed/30144045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12996 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|