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Application of activity-based probes to the study of enzymes involved in cancer progression

Many tumor cells have elevated levels of hydrolytic and proteolytic enzymes, presumably to aid in key processes such as angiogenesis, cancer cell invasion, and metastasis. Since the activities of these enzymes are often regulated by post-translational mechanisms, their functional roles in cancer pro...

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Detalhes bibliográficos
Main Authors: Paulick, Margot G., Bogyo, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474457/
https://ncbi.nlm.nih.gov/pubmed/18294838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2007.12.001
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