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Application of activity-based probes to the study of enzymes involved in cancer progression

Many tumor cells have elevated levels of hydrolytic and proteolytic enzymes, presumably to aid in key processes such as angiogenesis, cancer cell invasion, and metastasis. Since the activities of these enzymes are often regulated by post-translational mechanisms, their functional roles in cancer pro...

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Hlavní autoři: Paulick, Margot G., Bogyo, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474457/
https://ncbi.nlm.nih.gov/pubmed/18294838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2007.12.001
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