Ferrous iron-dependent drug delivery enables controlled and selective release of therapeutic agents in vivo

The precise targeting of cytotoxic agents to specific cell types or cellular compartments is of significant interest in medicine, with particular relevance for infectious diseases and cancer. Here, we describe a method to exploit aberrant levels of mobile ferrous iron (Fe(II)) for selective drug del...

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Bibliografiska uppgifter
Huvudupphovsmän: Deu, Edgar, Chen, Ingrid T., Lauterwasser, Erica M. W., Valderramos, Juan, Li, Hao, Edgington, Laura E., Renslo, Adam R., Bogyo, Matthew
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2013
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831501/
https://ncbi.nlm.nih.gov/pubmed/24145449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312782110
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