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Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor

Iron is essential to all life, and competition for this vital nutrient is central to host–pathogen interactions during infection. The opportunistic Gram-negative pathogen Pseudomonas aeruginosa utilizes a diverse array of iron-acquisition strategies, including those enabling import of extracellular...

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Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Blank, Brian R., Talukder, Poulami, Muir, Ryan K., Green, Erin R., Skaar, Eric P., Renslo, Adam R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880962/
https://ncbi.nlm.nih.gov/pubmed/31140267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.9b00057
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