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Crystal structure of LpxC from Pseudomonas aeruginosa complexed with the potent BB-78485 inhibitor
The cell wall in Gram-negative bacteria is surrounded by an outer membrane comprised of charged lipopolysaccharide (LPS) molecules that prevent entry of hydrophobic agents into the cell and protect the bacterium from many antibiotics. The hydrophobic anchor of LPS is lipid A, the biosynthesis of whi...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2248309/ https://ncbi.nlm.nih.gov/pubmed/18287278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.073324108 |
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