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Ferrous iron-dependent delivery of therapeutic agents to the malaria parasite
BACKGROUND: The malaria parasites Plasmodium falciparum and Plasmodium vivax generate significant concentrations of free unbound ferrous iron heme as a side product of hemoglobin degradation. The presence of these chemically reactive forms of iron, rare in healthy cells, presents an opportunity for...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3574796/ https://ncbi.nlm.nih.gov/pubmed/23234548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.174 |
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