Loading...

Ferrous iron-dependent delivery of therapeutic agents to the malaria parasite

BACKGROUND: The malaria parasites Plasmodium falciparum and Plasmodium vivax generate significant concentrations of free unbound ferrous iron heme as a side product of hemoglobin degradation. The presence of these chemically reactive forms of iron, rare in healthy cells, presents an opportunity for...

Full description

Saved in:
Bibliographic Details
Main Authors: Mahajan, Sumit S, Gut, Jiri, Rosenthal, Philip J, Renslo, Adam R
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574796/
https://ncbi.nlm.nih.gov/pubmed/23234548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.174
Tags: Add Tag
No Tags, Be the first to tag this record!