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Ferrous iron-dependent delivery of therapeutic agents to the malaria parasite

BACKGROUND: The malaria parasites Plasmodium falciparum and Plasmodium vivax generate significant concentrations of free unbound ferrous iron heme as a side product of hemoglobin degradation. The presence of these chemically reactive forms of iron, rare in healthy cells, presents an opportunity for...

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Détails bibliographiques
Auteurs principaux: Mahajan, Sumit S, Gut, Jiri, Rosenthal, Philip J, Renslo, Adam R
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574796/
https://ncbi.nlm.nih.gov/pubmed/23234548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.12.174
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