Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets

по Mahon, Olwyn R., Dunne, Aisling
Опубликовано в: Front Immunol (2018)

Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity

по Cunningham, Colm, Dunne, Aisling, Lopez-Rodriguez, Ana Belen
Опубликовано в: Neuroscientist (2018)

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling

по O'Rourke, Sinead A., Dunne, Aisling, Monaghan, Michael G.
Опубликовано в: Front Cardiovasc Med (2019)

Toll-like Receptor 3 (TLR3) Signaling Requires TLR4 Interactor with Leucine-rich Repeats (TRIL)

по Carpenter, Susan, Wochal, Paulina, Dunne, Aisling, O'Neill, Luke A. J.
Опубликовано 2011

Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1

по Campbell, Nicole K., Fitzgerald, Hannah K., Fletcher, Jean M., Dunne, Aisling
Опубликовано в: Front Immunol (2019)

Osteoarthritis-associated basic calcium phosphate crystals activate membrane proximal kinases in human innate immune cells

по Corr, Emma M., Cunningham, Clare C., Helbert, Laura, McCarthy, Geraldine M., Dunne, Aisling
Опубликовано в: Arthritis Res Ther (2017)

Activation of biliverdin-IXα reductase by inorganic phosphate and related anions

по Franklin, Edward, Browne, Seamus, Hayes, Jerrard, Boland, Coilin, Dunne, Aisling, Elliot, Gordon, Mantle, Timothy J.
Опубликовано 2007

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

по Gray, Pearl, Dunne, Aisling, Brikos, Constantinos, Jefferies, Caroline A., Doyle, Sarah L., O′Neill, Luke A. J.
Опубликовано в: J Biol Chem (2016)

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

по Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Опубликовано в: Glia (2015)

IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)

по Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Опубликовано 2010

IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal).

по Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Опубликовано в: J Biol Chem (2016)

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

по Campbell, Nicole K., Fitzgerald, Hannah K., Malara, Anna, Hambly, Roisin, Sweeney, Cheryl M., Kirby, Brian, Fletcher, Jean M., Dunne, Aisling
Опубликовано в: Sci Rep (2018)

Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages

по Campbell, Nicole K., Williams, David G., Fitzgerald, Hannah K., Barry, Paul J., Cunningham, Clare C., Nolan, Derek P., Dunne, Aisling
Опубликовано в: Front Immunol (2019)

Arabidopsis AtPARK13, Which Confers Thermotolerance, Targets Misfolded Proteins

по Basak, Indranil, Pal, Ramavati, Patil, Ketan S., Dunne, Aisling, Ho, Hsin-Pin, Lee, Sungsu, Peiris, Diluka, Maple-Grødem, Jodi, Odell, Mark, Chang, Emmanuel J., Larsen, Jan Petter, Møller, Simon G.
Опубликовано 2014

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

по Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm
Опубликовано в: Glia (2019)

NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1

по Miggin, Sinead M., Pålsson-McDermott, Eva, Dunne, Aisling, Jefferies, Caroline, Pinteaux, Emmanuel, Banahan, Kathy, Murphy, Caroline, Moynagh, Paul, Yamamoto, Masahiro, Akira, Shizuo, Rothwell, Nancy, Golenbock, Douglas, Fitzgerald, Katherine A., O'Neill, Luke A. J.
Опубликовано 2007

TRIL is involved in cytokine production in the brain following Escherichia coli infection

по Wochal, Paulina, Rathinam, Vijay A.K., Dunne, Aisling, Carlson, Thaddeus, Kuang, Wen, Seidl, Kathy J, Hall, J. Perry, Lin, Lih-Ling, Collins, Mary, Schattgen, Stefan A., MacKay, Christopher R., Fagundes, Caio T., Carpenter, Susan, Fitzgerald, Katherine A., O'Neill, Luke A.J.
Опубликовано в: J Immunol (2014)

Activation of the Nlrp3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

по Masters, Seth L., Dunne, Aisling, Subramanian, Shoba L., Hull, Rebecca L., Tannahill, Gillian M., Sharp, Fiona A., Becker, Christine, Franchi, Luigi, Yoshihara, Eiji, Chen, Zhe, Mullooly, Niamh, Mielke, Lisa A., Harris, James, Coll, Rebecca C., Mills, Kingston H. G., Mok, K. Hun, Newsholme, Philip, Nuñez, Gabriel, Yodoi, Junji, Kahn, Steven E., Lavelle, Ed C., O’Neill, Luke A.J.
Опубликовано 2010

A functional variant in TIRAP, also known as MAL, and protection against invasive pneumococcal disease, bacteraemia, malaria and tuberculosis

по Khor, Chiea C., Chapman, Stephen J., Vannberg, Fredrik O, Dunne, Aisling, Murphy, Caroline, Ling, Edmund Y, Frodsham, Angela J., Walley, Andrew J, Kyrieleis, Otto, Khan, Amir, Aucan, Christophe, Segal, Shelley, Moore, Catrin E., Knox, Kyle, Campbell, Sarah J., Lienhardt, Christian, Scott, Anthony, Aaby, Peter, Sow, Oumou Y., Grignani, Robert T., Sillah, Jackson, Sirugo, Girogio, Peshu, Nobert, Williams, Thomas N., Maitland, Kathryn, Davies, Robert J. O., Kwiatkowski, Dominic P., Day, Nicholas P., Yala, Djamel, Crook, Derrick W., Marsh, Kevin, Berkley, James A, O’Neill, Luke A.J., Hill, Adrian V. S.
Опубликовано 2007