Disease-Associated Particulates and Joint Inflammation; Mechanistic Insights and Potential Therapeutic Targets

Por Mahon, Olwyn R., Dunne, Aisling
Publicado no Front Immunol (2018)

Astrocytes: heterogeneous and dynamic phenotypes in neurodegeneration and innate immunity

Por Cunningham, Colm, Dunne, Aisling, Lopez-Rodriguez, Ana Belen
Publicado no Neuroscientist (2018)

The Role of Macrophages in the Infarcted Myocardium: Orchestrators of ECM Remodeling

Por O'Rourke, Sinead A., Dunne, Aisling, Monaghan, Michael G.
Publicado no Front Cardiovasc Med (2019)

Toll-like Receptor 3 (TLR3) Signaling Requires TLR4 Interactor with Leucine-rich Repeats (TRIL)

Por Carpenter, Susan, Wochal, Paulina, Dunne, Aisling, O'Neill, Luke A. J.
Publicado em 2011

Plant-Derived Polyphenols Modulate Human Dendritic Cell Metabolism and Immune Function via AMPK-Dependent Induction of Heme Oxygenase-1

Por Campbell, Nicole K., Fitzgerald, Hannah K., Fletcher, Jean M., Dunne, Aisling
Publicado no Front Immunol (2019)

Osteoarthritis-associated basic calcium phosphate crystals activate membrane proximal kinases in human innate immune cells

Por Corr, Emma M., Cunningham, Clare C., Helbert, Laura, McCarthy, Geraldine M., Dunne, Aisling
Publicado no Arthritis Res Ther (2017)

Activation of biliverdin-IXα reductase by inorganic phosphate and related anions

Por Franklin, Edward, Browne, Seamus, Hayes, Jerrard, Boland, Coilin, Dunne, Aisling, Elliot, Gordon, Mantle, Timothy J.
Publicado em 2007

MyD88 adapter-like (Mal) is phosphorylated by Bruton's tyrosine kinase during TLR2 and TLR4 signal transduction.

Por Gray, Pearl, Dunne, Aisling, Brikos, Constantinos, Jefferies, Caroline A., Doyle, Sarah L., O′Neill, Luke A. J.
Publicado no J Biol Chem (2016)

DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

Por Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Publicado no Glia (2015)

IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)

Por Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Publicado em 2010

IRAK1 and IRAK4 promote phosphorylation, ubiquitination, and degradation of MyD88 adaptor-like (Mal).

Por Dunne, Aisling, Carpenter, Susan, Brikos, Constantinos, Gray, Pearl, Strelow, Astrid, Wesche, Holger, Morrice, Nick, O'Neill, Luke A. J.
Publicado no J Biol Chem (2016)

Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment

Por Campbell, Nicole K., Fitzgerald, Hannah K., Malara, Anna, Hambly, Roisin, Sweeney, Cheryl M., Kirby, Brian, Fletcher, Jean M., Dunne, Aisling
Publicado no Sci Rep (2018)

Trypanosoma brucei Secreted Aromatic Ketoacids Activate the Nrf2/HO-1 Pathway and Suppress Pro-inflammatory Responses in Primary Murine Glia and Macrophages

Por Campbell, Nicole K., Williams, David G., Fitzgerald, Hannah K., Barry, Paul J., Cunningham, Clare C., Nolan, Derek P., Dunne, Aisling
Publicado no Front Immunol (2019)

Arabidopsis AtPARK13, Which Confers Thermotolerance, Targets Misfolded Proteins

Por Basak, Indranil, Pal, Ramavati, Patil, Ketan S., Dunne, Aisling, Ho, Hsin-Pin, Lee, Sungsu, Peiris, Diluka, Maple-Grødem, Jodi, Odell, Mark, Chang, Emmanuel J., Larsen, Jan Petter, Møller, Simon G.
Publicado em 2014

Chronic neurodegeneration induces type I interferon synthesis via STING, shaping microglial phenotype and accelerating disease progression

Por Nazmi, Arshed, Field, Robert H., Griffin, Eadaoin W., Haugh, Orla, Hennessy, Edel, Cox, Donal, Reis, Renata, Tortorelli, Lucas, Murray, Carol L., Lopez‐Rodriguez, Ana Belen, Jin, Lei, Lavelle, Ed C., Dunne, Aisling, Cunningham, Colm
Publicado no Glia (2019)

NF-κB activation by the Toll-IL-1 receptor domain protein MyD88 adapter-like is regulated by caspase-1

Por Miggin, Sinead M., Pålsson-McDermott, Eva, Dunne, Aisling, Jefferies, Caroline, Pinteaux, Emmanuel, Banahan, Kathy, Murphy, Caroline, Moynagh, Paul, Yamamoto, Masahiro, Akira, Shizuo, Rothwell, Nancy, Golenbock, Douglas, Fitzgerald, Katherine A., O'Neill, Luke A. J.
Publicado em 2007

TRIL is involved in cytokine production in the brain following Escherichia coli infection

Por Wochal, Paulina, Rathinam, Vijay A.K., Dunne, Aisling, Carlson, Thaddeus, Kuang, Wen, Seidl, Kathy J, Hall, J. Perry, Lin, Lih-Ling, Collins, Mary, Schattgen, Stefan A., MacKay, Christopher R., Fagundes, Caio T., Carpenter, Susan, Fitzgerald, Katherine A., O'Neill, Luke A.J.
Publicado no J Immunol (2014)

Activation of the Nlrp3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Por Masters, Seth L., Dunne, Aisling, Subramanian, Shoba L., Hull, Rebecca L., Tannahill, Gillian M., Sharp, Fiona A., Becker, Christine, Franchi, Luigi, Yoshihara, Eiji, Chen, Zhe, Mullooly, Niamh, Mielke, Lisa A., Harris, James, Coll, Rebecca C., Mills, Kingston H. G., Mok, K. Hun, Newsholme, Philip, Nuñez, Gabriel, Yodoi, Junji, Kahn, Steven E., Lavelle, Ed C., O’Neill, Luke A.J.
Publicado em 2010

A functional variant in TIRAP, also known as MAL, and protection against invasive pneumococcal disease, bacteraemia, malaria and tuberculosis

Por Khor, Chiea C., Chapman, Stephen J., Vannberg, Fredrik O, Dunne, Aisling, Murphy, Caroline, Ling, Edmund Y, Frodsham, Angela J., Walley, Andrew J, Kyrieleis, Otto, Khan, Amir, Aucan, Christophe, Segal, Shelley, Moore, Catrin E., Knox, Kyle, Campbell, Sarah J., Lienhardt, Christian, Scott, Anthony, Aaby, Peter, Sow, Oumou Y., Grignani, Robert T., Sillah, Jackson, Sirugo, Girogio, Peshu, Nobert, Williams, Thomas N., Maitland, Kathryn, Davies, Robert J. O., Kwiatkowski, Dominic P., Day, Nicholas P., Yala, Djamel, Crook, Derrick W., Marsh, Kevin, Berkley, James A, O’Neill, Luke A.J., Hill, Adrian V. S.
Publicado em 2007