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DNA sensors are expressed in astrocytes and microglia in vitro and are upregulated during gliosis in neurodegenerative disease

The detection of nucleic acids by the innate immune system is an essential host response during viral infection. In recent years, a number of immune sensors capable of recognizing cytosolic DNA have been identified and include the PYHIN family members AIM2, IFI16, and p204 as well as the enzyme, cGA...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Cox, Donal J., Field, Robert H., Williams, David G., Baran, Marcin, Bowie, Andrew G., Cunningham, Colm, Dunne, Aisling
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657478/
https://ncbi.nlm.nih.gov/pubmed/25627810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22786
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