TRIL is involved in cytokine production in the brain following Escherichia coli infection

TLR4 interactor with leucine-rich repeats (TRIL) is a brain-enriched accessory protein important in Toll-like receptor 3 and 4 signalling. Here we generated TRIL-deficient mice and examined TLR responses in vitro and in vivo. We found a role for TRIL in both TLR4 and TLR3 signalling in mixed glial c...

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Udgivet i:J Immunol
Main Authors: Wochal, Paulina, Rathinam, Vijay A.K., Dunne, Aisling, Carlson, Thaddeus, Kuang, Wen, Seidl, Kathy J, Hall, J. Perry, Lin, Lih-Ling, Collins, Mary, Schattgen, Stefan A., MacKay, Christopher R., Fagundes, Caio T., Carpenter, Susan, Fitzgerald, Katherine A., O'Neill, Luke A.J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503690/
https://ncbi.nlm.nih.gov/pubmed/25015823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302392
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