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Building unique bonds to fight misplaced DNA

A cyclic dinucleotide comprised of GMP and AMP was previously shown to be a key intermediate during activation of innate immune responses to cytosolic DNA. A report by Patel and Tuschl groups published in Cell reveals the structure of the enzyme involved in the synthesis of this second messenger and...

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Detalhes bibliográficos
Main Authors: Fagundes, Caio T, O'Neill, Luke A J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760622/
https://ncbi.nlm.nih.gov/pubmed/23774266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.81
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