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Activation of biliverdin-IXα reductase by inorganic phosphate and related anions

The effect of pH on the initial-rate kinetic behaviour of BVR-A (biliverdin-IXα reductase) exhibits an alkaline optimum with NADPH as cofactor, but a neutral optimum with NADH as cofactor. This has been described as dual cofactor and dual pH dependent behaviour; however, no mechanism has been descri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Franklin, Edward, Browne, Seamus, Hayes, Jerrard, Boland, Coilin, Dunne, Aisling, Elliot, Gordon, Mantle, Timothy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Portland Press Ltd. 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925240/
https://ncbi.nlm.nih.gov/pubmed/17402939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061651
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