טוען...
Enzymatic activity and thermodynamic stability of biliverdin IXβ reductase are maintained by an active site serine
Biliverdin reductase IXβ (BLVRB) is a crucial enzyme in heme metabolism. Recent studies in humans have identified a loss-of-function mutation (Ser111Leu) that unmasks a fundamentally important role in hematopoiesis. We have applied experimental and thermodynamic modeling studies to provide further i...
שמור ב:
| הוצא לאור ב: | Chemistry |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293602/ https://ncbi.nlm.nih.gov/pubmed/27897348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201604517 |
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